Diabetes science/medical journalism
Learn more about
- Background and current project status
- In this Issue - Diabetes Care
(ADA journal) - In this Issue - Diabetes
(ADA journal) - Diabetes is Primary
(digested reads in ADA journals)
Overview, background and current project status
I have been writing about diabetes research since early 2015 in the form of the ‘In this Issue’ section of the Diabetes and Diabetes Care journals of the American Diabetes Association (ADA). The section is part of the 'front matter' of the journals.
The first version was published in June 2015 and the most recent version is for the July 2020 issue of both journals. You can find the complete list of articles for these journals below.
I have also written the ‘Diabetes is Primary’ section for Clinical Diabetes and Diabetes Spectrum. These articles are research digests highlighting developments over three month periods.
*At the moment, this project is paused, mainly because of the fallout from the COVID-19/SARS-CoV-2 pandemic. We are planning to restart in early 2021.*
You can find the complete list of articles, summaries and digests that are published so far in the ADA journals below. There are about 650 individuals items in total.
Diabetes Care - In this Issue
Diabetes Care, as a journal, is intended for healthcare practitioners and aims to increase knowledge, research and the promotion of better management of individuals with diabetes.
It covers original research with a clinical orientation as well as the publication of statements, consensus reports, clinical review articles, letters and health/medical news. Find out much more about Diabetes Care on the journal's website.
The 'In this Issue' section of Diabetes Care, that I have written for the past five years, is published every month as the first article of each issue. The section highlights, in summary form, four papers that appear in that month's issue. They are usually chosen on the basis of novelty or likely clinical impact.
Each summary consists of about 300 words and aims to bring out the potential clinical relevance of the research in a format that is quick and easy to read.
2020 (vol 43, issues 1-7)
- COVID-19 and diabetes—worrying developments from early reports
- Clinical characteristics and risks for COVID-19 patients with diabetes in Wuhan, China
- ADA/EASD consensus report on precision medicine in diabetes
- Type 2 diabetes prevention programs and sugar taxation are likely cost-effective: systematic review
- DOI: https://doi.org/10.2337/dc20ti07
- PDF: July 2020—In this Issue of Diabetes Care
- Combination of liraglutide and canagliflozin reduces weight in type 2 diabetes but not HbA1c
- Troponins predict mortality risk in older individuals with diabetes
- Meaningful weight loss linked to a wide range of cardiorenal risk reduction in diabetes and obesity
- Continuous glucose monitoring data reveal detailed glucose differences during pregnancy in type 1 diabetes
- DOI: https://doi.org/10.2337/dc20-ti06
- PDF: June 2020—In this Issue of Diabetes Care
- Medicaid expansion has resulted in improvements in diabetes outcomes in the US
- Weight loss with liraglutide in individuals with increased weight and type 2 diabetes treated with insulin
- Hyperglycemia crisis events increased in the US in the period 2009-2015
- Dietary saturated fat compared to free sugars for liver, metabolic risks
- DOI: https://doi.org/10.2337/dc20-ti05
- PDF: May 2020—In this Issue of Diabetes Care
- Elevated glucose levels tied to risks for microvascular complications in prediabetes
- Intensive glycemic control also reduces risks of recurrent CVD events in type 1 diabetes
- Dysglycemia and coronary artery disease guidelines: a “job half done”
- Longer lifetime duration of lactation reduces risk of type 2 diabetes following gestational diabetes mellitus
- DOI: https://doi.org/10.2337/dc20-ti04
- PDF: April 2020—In this Issue of Diabetes Care
- Global mechanisms proposed for cardioprotective effects of SGLT2 inhibitors
- Oxygen therapy improves diabetic ulcer wound healing: RCT data
- “A bidirectional relationship”: severe hypoglycemia and cardiovascular events
- Artificial pancreas and a combination of rapid insulin/pramlintide improves glucose control
- DOI: https://doi.org/10.2337/dc20-ti03
- PDF: March 2020—In this Issue of Diabetes Care
- Recommendations to maintain levels of red meat consumption “not justified”
- Treatment improvements with intermittently scanned continuous glucose monitoring in type 1 diabetes
- Empagliflozin tied to liver fat reductions in recent-onset, well-controlled type 2 diabetes
- Economic and clinical burden of NASH in type 2 diabetes forecast to rise in next 20 years
- DOI: https://doi.org/10.2337/dc20-ti02
- PDF: February 2020—In this Issue of Diabetes Care
- Dietary fat affects postprandial glucose levels—implications for insulin dosing in type 1 diabetes
- UK NHS DPP: improvements in weight and HbA1c consistent with recent trial evidence, retention an issue in certain groups
- Real-time continuous glucose monitoring reduces hypoglycemia in type 1 diabetes
- Diagnosing MODY: testing for autoantibodies and family history are key
- DOI: https://doi.org/10.2337/dc20-ti01
- PDF: January 2020—In this Issue of Diabetes Care
2015-2019 (vols 38 - 42)
- December 2019 - Oral semaglutide (PIONEER 2) | Weight, minorities and diabetes risks | Diabetes risks and sugary drinks | Glycemic control (real world data)
- November 2019 - Insulin pumps and CGM usage | Oxygen therapy | GRADE study | Diabetes Programs in Hong Kong
- October 2019 - Metformin in prediabetes | Sotagliflozin | Diabetes and frailty | Cardiometabolic risks
- September 2019 - Oral semaglutide (PIONEER 1) | Diabetes economic burden in US |Heart failure implications | Reversal of prediabetes (implications)
- August 2019 - CGM data recommendations | Physical activity | Mediterranean diet delays diabetes medicines | Mediterranneann diet improves cognitive health
- July 2019 - CVD risk in DCCT/EDIC studies | CBT, exercise for diabetes remission | Insulin variability in kids | Cognitive impairment in older age
- June 2019 - Diabetic ketoacidosis and SGLT inhibition | Dapagliflozin and glucose | Bluetooth insulin pen cap | Anti-GAD antibodies
- May 2019 - PREDIMED-Plus initial results | Renal disease factors in T1D | Retinopathy risks | Seasonal treatment outcomes
- April 2019 - Insulin dosing and cardiometabolic risks | Artificial pancreas progress | Preventing diabetes with metformin | Insulin pump therapy questioned
- March 2019 - Gestational diabetes | Ketoacidosis and cognition | Blood glucose metrics and complications | Intensive treatment of glycemia
- February 2019 - Bariatric surgery | Genetic risk scores | Pancreas volumes (x2)
- January 2019 - End stage renal disease in Sweden | Biomarkers and MODY risks | Amputation rates up in US | Neuropathy and HbA1C
- December 2018 - Hyperglycemia guidance | Hypoglycemia risks | Insulin pump therapy | Economic costs of diabetes in US
- November 2018 - ‘Confusion to clarity’ on glucose control | Declining US mortality due to CVD | Gut microbiota, T1D and MODY2 | CGM and retinopathy risks
- October 2018 - Dietary counselling outcomes | Walking and obesity | Basal insulins in head-to-head | Urological complications
- September 2018 - Position statement on type 1 diabetes | Diabetes distress | Genetic risk scores | Hospital admissions for ketoacidosis
- August 2018 - Diabetic ketoacidosis rates and costs | SGLT2 inhibitor combos | Hypoglycemia awareness program | Saturated fat harms in obesity/liver disease
- July 2018 - Artificial pancreas progress | Diabetes prevention progress | Diet and gestational diabetes | C-peptide declines in type 1 diabetes
- June 2018 - Insulin affordability | Surgery outcomes and diabetes | HbA1c variations | Multicomponent care in diabetes
- May 2018 - ACA insurance and diabetes | Economic productivity and diabetes | Insulins and HbA1c | Weight changes and diabetes risks
- April 2018 - Artificial pancreas optimisation | Diet, exercise reduce diabetes risks in China | Bariatric surgery, obesity and type 2 diabetes | Diabetic kidney disease
- March 2018 - Gut targeted niacin and prediabetes | Kidney disease universal in T1D | Moving more and prediabetes | ESRD in Norway
- February 2018 - Cost-effectiveness of diabetes care program | T2D genetic variant in T1D | Exenatide and drug delivery device | CGM and HbA1c
- January 2018 - 1-hour glucose tolerance test | Telemedicine and diabetic foot ulcers | 5-year evaluation of diabetes program | Diabetes drug usage in US
- December 2017 - BMI, diet, exercise and diabetes in China | DCCT/EDIC update | Offspring insulin resistance and GDM | Exercise and T1D
- November 2017 - Skipping breakfast | Metformin non-adherence | Bariatric surgery and GLP-1 | Cognitive decline and hyperglycemia
- October 2017 - CDC Diabetes Prevention Program | Secure messaging and diabetes | Text messaging and glucose control | Bariatric surgery risks and diabetes
- September 2017 - Online gaming and diabetes | Glucose recording accuracy and GDM | Diabetes rates in US | Predicting heart failure risk
- August 2017 - 20 year autoantibody profiles | Red meat | Distinguishing monogenic diabetes | Genetic risk variant for T2D
- July 2017 - Glucose peaks and cognitive function | Metabolic profiles and child diabetes risks | Telemedicine and diabetes | Lifestyle/metformin and cognitive decline
- June 2017 - Driving and diabetes | Metformin and complications | Glycemic variability and microvascular outcomes | Hypoglycemia with insulin pumps and CGM
- May 2017 - Diabetes risks | Cardiac arrhythmia and hypoglycemia | hyperglycemia and pregnancy | Genetically raised blood glucose
- April 2017 - Dyslipidemia in T1D | Care quality in older adults | CGM compared to standard glucose monitoring | Improved glycemic control with insulin
- March 2017 - Diabetic retinopathy statement | Ethnicity and type 2 diabetes | Infant formula and type 1 diabetes risks | Combo drug therapy and diabetes
- February 2017 - Sitagliptin risks | Hypoglycemia hospitalisation in Denmark | Thromboembalism risks | Metformin biomarker
- January 2017 - Blood glucose levels and clinical trials | Statement on diabetic neuropathy | Neuropathy and later cardiovascular risks | Metformin and gut microbes
- December 2016 - Duodenal mucosal resurfacing | Resveratrol and insulin sensitivity | Blood pressure and renal outcomes in T1D | Sitagliptin and outcomes
- November 2016 - Genetic predictors of cardiovascular mortality | metformin and sitagliptin | Insulin and lixisenatide | Fibroblast growth factor 21
- October 2016 - Gastric bypass and eating | Genetic variant for glucose metabolism | Exenatide dosing | Pioglitazone and risks
- September 2016 - Lixisenatide/insulin combo and HbA1c | β-cell autoantibodies and T1D risks | T2D mortality in China | Blunted insulin action
- August 2016 - Type 1 diabetes mortality rates | HbA1c research gaps, opportunities | Lixisenatide and HbA1c reductions | Hidden information in glucose tolerance tests
- July 2016 - Explaining T2D rates in minorities | Artificial pancreas trials | Cognitive function and diabetic foot | Precision Medicine Initiative
- June 2016 - Statement on metabolic surgery in T2D | Improved bariatric surgery outcomes | Modest glycemic benefits with liraglutide | Glucose variability and exenatide
- May 2016 - Hospitalisation risks with diabetes/prediabetes | Weight loss and reversible T2D | Intensive glucose control and risk of ESRD | Sleep deprivation and cognition
- April 2016 - Hypoglycemia (un)awareness | Glucagon nasal spray | C-peptide for neuropathy | Uric acid levels and T1D
- March 2016 - Underestimated hypoglycemia rates | Genetic risk factors for detection | Diabetes rates in Asia and the Pacific | CVD/diabetes risk factors and atherosclerosis
- February 2016 - Reclassifying diabetes | Semaglutide dosing | Metformin gut mechamisms | Liraglutide and CNS responses
- January 2016 - Pregnancy outcomes in early GDM | Alogliptin, atherosclerosis in T2D | Zinc transporter 8 autoantibodies | Cognitive issues and cardiovascular outcomes
- December 2015 - SGLT2 inhibitor history | HbA1c and durable glycemic control | Gestational age, birth weight and T1D | Depression and diabetes
- November 2015 - Sleep disturbance and T2D | Environmental factors in Mexico and diabetes | Insulin dosing in ACCORD | Mediterranean diet and retinopathy
- October 2015 - Lactobacillus and insulin secretion | Breakfast and diabetes | Diabetic ketoacidosis rates
- September 2015 - SGLT2 inhibitors and diabetic ketoacidosis | Alcohol consumption and T2D risks | Cognitive impairment and T1D diagnosis | Stem cells and T2D
- August 2015 - Exercise and type 2 diabetes | Screening for CVD risk in diabetes | Sclerostin and prediabetes
- July 2015 - Medical record detail | Markers and diabetes diagnosis | CGM patterns identify large-for-gestational age infants | Glycemic control and school grades
- June 2015 - Antipsychotic drugs and T1D | Acute pancreatitis and incretin-based therapy | HbA1c and ACCORD | Weight management and diabetes
Diabetes - In this Issue
Diabetes, the journal, is focussed on original research about the (patho-)physiology of diabetes. Published research in this journal tends to be more fundamental and covers any aspect of laboratory, animal and human research.
Investigative reports usually cover pathogenesis of diabetes and complications, metabolism and mechanisms. The journal also focusses on biochemical and molecular aspects of biological processes associated with diabetes and its complications. Find out more about the aims of Diabetes at the journal's website.
The 'In this Issue' section of Diabetes, that I have written for the past five years, is published every month and is the first article in each issue. The section comprises of four summaries of papers that are considered to be highlights in each issue.
Each summary is about 300 words in length and as well as describing the outcomes of the research, they try to bring out the biological and potentially clinical significance of each investigation. With the readership of this journal in mind, each summary is written in a format that is accessible and quick to read.
2020 (vol 69, issues 1-7)
- Hybrid insulin peptides present in type 1 diabetes might explain loss of insulin
- NOX4-generated H2O2 is required for glucose-stimulated insulin secretion
- β-cell failure linked to sustained intracellular Ca2+ increases and overnutrition
- α-Klotho involvement in central regulation of metabolism: mechanisms and therapeutic options
- DOI: https://doi.org/10.2337/db20-ti07
- PDF: July 2020—In this Issue of Diabetes
- Hyperuricemia linked to diabetes development in urjcase knockout mice
- Myo-inositol oxygenase key to tubulointerstitial injury in diabetes
- Adipose triglyceride lipase identified as key factor in β-cell dysfunction in diabetes
- Central KATP channels modulate the suppression of endogenous glucose production by hyperglycemia
- DOI: https://doi.org/10.2337/db20-ti06
- PDF: June 2020—In this Issue of Diabetes
- Chemical scaffold identified to potentially reverse β-cell dysfunction due to glucolipotoxicity in diabetes
- Vitamin D receptor in islets downregulated during diabetes development
- Proinsulin interactions explored as a potential drug target for diabetes
- Risk factors identified for neuropathy complications in type 1 diabetes
- DOI: https://doi.org/10.2337/db20-ti05
- PDF: May 2020—In this Issue of Diabetes
- PPARA polymorphism can identify patients with type 2 diabetes who would benefit from fenofibrate treatment
- Insulin and glucagon levels do not explain increased endogenous glucose production with SGLT2 inhibitors
- Novel low-frequency genetic variants have large effects on type 1 diabetes risks
- “Curative potential”: immune cells and gene expression levels in LADA pancreases explored
- DOI: https://doi.org/10.2337/db20-ti04
- PDF: April 2020—In this Issue of Diabetes
- Type 1 diabetes: different metabolic profiles prior to seroconversion to IAA or GADA
- HB-EGF signalling axis required for glucose-stimulated β-cell proliferation
- Placental DNA methylation linked to maternal insulin sensitivity in pregnancy
- Gremlin 1: A therapeutic target for insulin resistance and complications of type 2 diabetes
- DOI: https://doi.org/10.2337/db20-ti03
- PDF: March 2020—In this Issue of Diabetes
- Multiple data streams identify new features involved in early type 1 diabetes development
- Prevalence of lipodystrophy in US population likely to be underestimated
- Metabolic inflexibility to fat intake may explain later weight increases in healthy adults
- HMG-CoA reductase involved in adipose tissue macrophage recruitment, inflammation and insulin resistance
- DOI: https://doi.org/10.2337/db20-ti02
- PDF: February 2020—In this Issue of Diabetes
- Diabetes prevention improves cardiovascular risk factors regardless of genetic risk for heart disease
- More genetic variants associated with declines in first-phase insulin response
- RNF20: a potential target in obesity-induced metabolic disorders
- High prevalence of monogenic diabetes in Han Chinese diagnosed with type 1 diabetes
- DOI: https://doi.org/10.2337/db20-ti01
- PDF: January 2020—In this Issue of Diabetes
2015-2019 (vols 64 - 68)
- December 2019 - Methylation features in early diabetes | Nephropathy and transcriptomics | ABO blood type and diabetes risks | NEUROD1 and stem cells
- November 2019 - White matter changes and cognitive impairments | CACNB2 gene and retinopathy | Wound healing in T1D | Sarm1: target for neuropathy
- October 2019 - Montelukast for retinopathy | Foreign-body reaction to CGM | Impaired metabolism in neuropathy | Gene signature ID’d prior to T1D development
- September 2019 - Treatment for insulin resistance in obesity | New autoantibody for T1D prediction | Early stage development in pancreas | Hybrid insulin peptides
- August 2019 - High fat intake before pregnancy | “Causal residues” and T1D risk | Gene locus predicts risk of neuropathy | hyperinsulinemia and insulin resistance
- July 2019 - Fluoxetine and diabetic foot wound | Urocortin 2 treatment in T2D, obesity | Genetic regulation of insulin sensitivity | AMPK and muscle glucose uptake
- June 2019 - FGF19 and bariatric surgery | Anti-thymocyte globulin therapy | Surgical denervation | Hyperuricemia linked to obesity
- May 2019 - Enteroendocrine cells and treating diabetes, obesity | Older age and α-cells | Monosodium urate and retinopathy risks | Melatonin and brown adipose tissue
- April 2019 - Unaccounted for risk for T1D | QC system in β-cells | Genetic determinants of HbA1c | Risks for offspring following gestational diabetes
- March 2019 - Genetic regions associated with fulminant T1D | FoxOs and muscle atrophy in T1D | Retionopathy pathways | Prostaglandin signalling in gastroparesis
- February 2019 - WASH and islet glucose homeostasis | Novel peptides and nephropathy | Perturbations decades before diabetes diagnosis | Family clustering and renal decline
- January 2019 - PAX8 and gestational diabetes | Autoimmunity profiling and T1D | IGFBP-2 and T2D risks | Brain glucose levels and hyperglycemia
- December 2018 - Transforming α-cells into β-cells | Insm1 regulates β-cells | Glycemia in pregnancy | Induced hyperglycemia and glucose metabolism
- November 2018 - Krüppel-like factor 6 and podocyte loss | Effector T cells and T1D remission (in mice) | IgM prevents, reverses T1D (in mice) | β-cell workload
- October 2018 - New nephropathy mouse model | Energy expenditure in obesity | Noninvasive tracer method to determine β-cell mass | Precision Medicine and T2D
- September 2018 - IDO1 impairment precedes β-cell destruction | New mouse model for atherosclerosis | Stress recovery for β-cells | Biomarker T-cells in T1D
- August 2018 - Elastin-derived peptides | Combo-therapy and neuropathy | GLP1 receptor and improved glucose tolerance | Antigen-specific immunotherapy (review)
- July 2018 - Genetics and kidney disease | PI3K in obesity and insulin resistance | T1D prevention | Hypoglycemia prevention
- June 2018 - Sleeve gastrectomy and glycemia | β-cells and neoepitopes | Oxyntomodulin and glucose homeostasis | Pharmacology of insulins
- May 2018 - MicroRNAs and HbA1c in T1D | Catestatin improves glucose, insulin (in mice) | Fetal influenced by genetics, maternal glucose | Nephropathy biomarkers
- April 2018 - Novel islet cell population | Noncoding RNA controls glucose and fat | SRGAP2a, a key gene in nephropathy | MAMs: new target for glucose homeostatsis
- March 2018 - MondoA in human β-cells | SRp55 controls β-cell function/survival | DPP-4 inhibitors and wound healing | Perspective on insulin secretion
- February 2018 - In vivo imaging of β-cell mass | Glucocorticoids and insulin secretion | Reduced glucose uptake in multiple tissues | Genetic influences on BMI
- January 2018 - Metformin/AICAR in neuropathy | REDD1 prevents vision issues | Glycation gap and complications | Undiscovered genetic mutations
- December 2017 - Granzyme A deficiency breaks immune tolerance | Eye test to detect cognitive decline | Autoimmunity to type 1 diabetes | β-cell destruction mechanism
- November 2017 - IGF2, new therapeutic target in T2D | Gene targets in T2D | Adipose tissue remodelling after bariatric surgery | Autonomic failure and morphine
- October 2017 - New pathway to tackle hyperglycemia | Nox5 and Nephrology | Organic pollutants inhibit β-cell function | Physical activity and weight gain risk
- September 2017 - Kidney gluconeogenesis mechanisms | Mechanisms of genetic variant in T2D | Empagliflozin and prediabetes | Hypoglycemia and glucose uptake
- August 2017 - Trapping T cells | ACOT1 and fat metabolism | GLP-1 secretion mechanisms | Genetic variant and heart disease risks
- July 2017 - GDF11 for treating T2D | Exercise and miR-29 | Hypoglycemia risks with high intensity exercise | Empagliflozin and glucose excretion
- June 2017 - Stem cells and beige adipose tissue | Hypoglycemia awareness and exercise | GPR119 and insulin secretion | DNA methylation in T2D
- May 2017 - Islet transplantation and Sphingosine kinase 1 | Converting α-cells to β-cells |T1D and painful neuropathy
- April 2017 - Vagus nerve stimulation and glucose metabolism | Coordinated insulin and glucose response | Obesity prevention? | DNA methylation and islet cells
- March 2017 - GLUT4 in the brain | Brain hyperconnectivity | Sex hormones and T2D risks | Insulin sensitivity after exercise
- February 2017 - Glucocorticoid receptors and energy metabolism | Oxytocin and glucose | Follicular T helper cells and T1D diagnosis | Blood pressure and T2D
- January 2017 - Thermoregulation in obesity | Calorie restriction in T2D | Inosital-requiring enzyme 1 and diabetic wounds | Mitochondrial oxidative capacity and prediabetes
- December 2016 - Insulin resistance and metformin | Metformin metabolites | Magnetic resonance spectroscopy and metformin | Advanced glycation end products
- November 2016 - Insulin resistance reversal | Standard process for islet transplants | Amylase levels and energy production | IGF axis and gestational diabetes diagnosis
- October 2016 - Muscle myopathy in T1D | Muscle atrophy and bed rest | Exercise and insulin sensitivity | DAG accumulation and insulin sensitivity
- September 2016 - Endothelial dysfunction and hyaluronidase | Sulfonylurea safety in T2D | NOV/CCN3 for insulin resistance in obesity | Gestational diabetes and type 2 diabetes
- August 2016 - Atrasentan mechanisms | Hyaluronan and T1D | GLP-1 and other mediators of DPP-4 inhibition | Brain networks in prediabetes and T2D
- July 2016 - Brain responses to sugars in obesity | Exercise capacity and Prmt7 deficiency | Weight gain and autoimmunity | n-3 fatty acids and glycemic control
- June 2016 - 2015 Banting Lecture (adipose tissue) | 2015 Edwin Bierman Award (atherosclerosis in diabetes) | Tetraspanin-7 autoantibody target | AMPK and atherosclerosis | Insulin and fat secretion from liver
- May 2016 - Hypothyroidism and pancreatic stem cells | Cold exposure and wasting energy in obesity | AMPK signaling intact in T2D | β-cell destruction in T1D
- April 2016 - Rapamycin blocks thermogenesis | Apoptosis and chronic kidney disease | Treg gene signature biomarker for T1D | Thiamine transporter gene and T1D microvascular complications
- March 2016 - Podocytes and proteinuria in nephropathy | Insulitis and T1D | Insulin-independent target for diabetes | Gut origin of glucagon secretion
- February 2016 - Stem cells and diabetic foot | β-cell burnout | Aspirin and T1D | Perspective on gaseous signalling molecules
- January 2016 - T1D and Epstein-Barr virus | microRNAs and retinopathy | Biomarker for CVD and mortality | Cardiovascular control and hypoglycemia
- December 2015 - Diabetes and the microbiome | Mechanisms of pain in neuropathy | Antibody therapy for T1D remission | Autologous cell therapy
- November 2015 - Sweetness suppression by leptin | eNOS and atherosclerosis | Memory and learning loss in diabetes | Gastric bypass improves insulin and fitness outcomes
- October 2015 - Calcium sensitivity in diabetic heart muscle | Vaccine for T1D | Portal vein delivery of insulin | Kallikrein-Kinin system and diabetic macular edema
- September 2015 - Transcriptomics of α- and β-cells | Mitochondrial function and obesity | HDL cholesterol and T2D | microRNA and renal function in T1D
- August 2015 - Nitric oxide signalling and inflammation | Thrifty vs spendthrift energy expenditure | Staphylococcus aureus and diabetic foot | Plerixafor and stem cells
- July 2015 - Endostatin and obesity | Exenatide and vasodilation in T2D | Hypoglycemia and vascular outcomes | GLP-1 response in prediabetes and T2D
- June 2015 - Metformin and atherosclerosis | Low-dose IL-2 therapy in T1D | Brain insulin resistance and Alzheimer’s disease | Exercise, AICAR and insulin
Clinical Diabetes - Diabetes is Primary: News and Notes for Primary Care Providers
Clinical Diabetes provides primary care providers and clinicians with information on advances in the care for people with diabetes. In terms of the Diabetes is Primary section, which I have been writing for the past few years, the aim is to provide a digest of advances in various areas of diabetes care and research over quarterly periods.
The section covers broad areas such as highlights from the journals, treatments and therapies, the marketplace, conference spotlight and news from the American Diabetes Association (ADA). As such the digest/column covers very broad sweeps of many areas of diabetes and the care of people with diabetes.
2020 (vol 38, issues 1 - 3)
- From the journals - COVID-19 and diabetes | Obesity and COVID-19 severity risk
- Treatments and Therapies - Dapagliflozin tested in COVID-19 patients | "Overwhelming efficacy" - DAPA-CKD trial stopped early
- Marketplace - telehealth implementation and diabetes care
- ADA News
- Conference Spotlight - The going virtual edition (current status of diabetes conferences in the face of a pandemic)
- DOI: https://doi.org/10.2337/cd20-dp03
- PDF: July 2020—Diabetes is Primary - News and Notes for Primary Care Providers
- From the journals - Insulin affordability | WHO launchers prequalification for biosimiliar insulins | Illicit trading of diabetes treatments
- Treatments and therapies - Lipid profile predicts type 2 diabetes risk better than obesity | Three daily meals (not six) tied to better diabetes outcomes
- Marketplace - Most diabetes apps lack vital guidance on taking action
- ADA News
- Conference spotlight - Basic clinical and laboratory measurements can predict chronic kidney disease
- DOI: https://doi.org/10.2337/cd20-dp02
- PDF: April 2020—Diabetes is Primary - News and Notes for Primary Care Providers
- From the journals - Five markers to detect individuals with high risk for diabetes | Referrals to diabetes prevention program remain low
- Treatments and therapies - Type 2 diabetes affects heart structure and risks for failure | Federal survey data illuminate nonadherence due to diabetes drug costs
- Marketplace - Random plasma glucose tests may detect future diabetes risk
- ADA News
- Conference spotlight - Dapagliflozin in pivot towards global heart benefits | Signs of adults type 2 diabetes detected in children aged 8+ years
- DOI: https://doi.org/10.2337/cd20-dp01
- PDF: January 2020—Diabetes is Primary - News and Notes for Primary Care Providers
2019 (vol 37, issues 1 - 4)
- From the journals - Drug adherence in diabetes: old story, new developments | Texting and drug adherence | Adherence and accurate measurement
- Conference spotlight - Inpatient diabetic ketoacidosis mortality risk is higher at weekends | No major difference in cardiovascular outcomes for linagliptin versus glimepiride | Linagliptin found to be safe across levels of renal function and age-groups | Oral semaglutide has no added cardiovascular risk compared to placebo | Dulaglutide reduces cardiac events in type 2 diabetes | Additional reports
- Marketplace - Patients warned about “DIY” artificial pancreas setups | Use of flash continuous glucose monitoring leads to improved glycemic outcomes and greater treatment satisfaction
- Treatments and therapies - Canagliflozin reduces risk of kidney failure in type 2 diabetes
- ADA News
- DOI: https://doi.org/10.2337/cd19-0057
- PDF: October 2019—Diabetes is Primary - News and Notes for Primary Care Providers
- From the journals - Topical corticosteroids and type 2 diabetes risk | Rotavirus vaccine and type 1 diabetes: a link? | Beware the influence of influencers on kids’ snacking
- Treatments and therapies - DiRECT at year 2: sustained type 2 diabetes remission with weight loss | Insulin costs double in four years
- Marketplace - FDA warns against using pre-owned or used glucose test strips | Artificial pancreas system works for very young children | Many young patients have trouble using artificial pancreas system
- ADA News
- Conference spotlight - Large population study reveals consequences of severe obesity
- DOI: https://doi.org/10.2337/cd19-0027
- PDF: July 2019—Diabetes is Primary - News and Notes for Primary Care Providers
- From the journals - New guidance on exercise and type 2 diabetes | Even prediabetes increases cardiovascular risk
- Treatments and therapies - Sodium-glucose cotransporter 2 inhibitors: developments, risk assessments, and approvals | Liraglutide: real-world data support cardiovascular risk reduction
- Marketplace - FDA approves placement of Senseonics’ continuous glucose monitoring device by certified providers | Ready-to-use glucagon rescue pen moves closer to approval | Research continues into skin autofluorescence to predict diabetes risk
- Conference spotlight - Sodium-glucose cotransporter 2 inhibitors featured at American Heart Association meeting | And finally, ultrasound for diabetes screening
- ADA News
- DOI: https://doi.org/10.2337/cd19-0010
- PDF: April 2019—Diabetes is Primary - News and Notes for Primary Care Providers
- From the journals - Infections and poor glycemic control in diabetes | CVD mortality in patients with and without diabetes
- Treatments and therapies - “Twincretins”: trial finds reductions in A1C and weight with new dual incretin | EASE Research Program: empagliflozin offers benefits in type 1 diabetes | HARMONY Outcomes Study: albiglutide cuts cardiovascular risk in type 2 diabetes
- Marketplace - Closed-loop artificial pancreas system improves glycemic control and reduces hypoglycemia risk | FDA issues warning on the proper use of insulin pen needles
- ADA News
- Conference spotlight - EASD 2018
- DOI: https://doi.org/10.2337/cd18-0098
- PDF: January 2019—Diabetes is Primary - News and Notes for Primary Care Providers
2018 (vol 36, issues 1 - 4)
- From the journals - Self-monitoring of blood glucose in non-insulin-treated type 2 diabetes
- Treatments and therapies - Empagliflozin plus insulin | Dulaglutide | Insulin glargine | Oral semaglutide
- ADA News
- Marketplace - Accuracy of blood glucose meters questioned | Eversense implantable CGM receives approval for up to 90 days’ usage | Head-to-head accuracy comparison reported for three CGM devices
- Coding, regulations and reimbursements - New ICD-11 codes released—all 55,000 of them
- Conference spotlight - Risk of autism spectrum disorders in children of mothers with diabetes | Intensive treatment of type 2 diabetes is cost effective
- DOI: https://doi.org/10.2337/cd18-0072
- PDF: October 2018—Diabetes is Primary - News and Notes for Primary Care Providers
- From the journals - Diabetes and surgery risks | Intensive lifestyle intervention and disability in type 2 diabetes | Few adults follow nutrition and lifestyle recommendations to avoid diabetes | β-blockers and all-cause mortality in people with diabetes | Pedometers can increase exercise over the long term
- Treatments and therapies - Drugs roundup
- Marketplace - Technology roundup | Cost effectiveness of CGM device evaluated
- ADA News
- DOI: https://doi.org/10.2337/cd18-0036
- PDF: July 2018—Diabetes is Primary - News and Notes for Primary Care Providers
- From the journals - Increased risks of infections in diabetes | Dipeptidyl peptidase-4 inhibitors for diabetic foot ulcers | Gestational diabetes: very high risk for type 2 diabetes and heart disease
- Treatments and therapies - Subcutaneous exenatide delivery device proven in phase 3 trial | Insulin tolerance test predicts efficacy of liraglutide in type 2 diabetes | New sodium-glucose cotransporter 2 inhibitor gains FDA approval
- Coding, regulations and reimbursements - Medicare extends coverage to two diabetes devices
- ADA News
- Marketplace - Diabetes foot ulcers: A novel dressing and two new therapeutic devices
- Conference spotlight - Continuous glucose monitoring recommendations published
- DOI: https://doi.org/10.2337/cd18-0007
- PDF: April 2018—Diabetes is Primary - News and Notes for Primary Care Providers
- From the journals - Poor adherence cuts real-world effectiveness of diabetes drugs | In the news: soaring rates of obesity in children | New analyses: Diabetes-related morality in Germany and diabetes rates in China
- Treatments and therapies - Semaglutide: injectable formulation on track for approval, success reported with oral formulation, and efficacy as obesity therapy explored
- ADA News
- Marketplace - Patients referred to weight management classes might reduce their risk of type 2 diabetes | Artificial pancreas succeeds, but what drives uptake of the technology
- DOI: https://doi.org/10.2337/cd17-0123
- PDF: January 2018—Diabetes is Primary - News and Notes for Primary Care Providers
2017 (vol 35, issues 4 - 5)
- From the journals - Drugs work when patients take them | Is technology the answer to this? | About skipping breakfast
- ADA News
- Good to know: drug target hunting
- Marketplace - Progression of and FDA approval for artificial pancreas technology
- Treatment and therapies - Artificial pancreas system offers improved glycemic control during winter sports | FOURIER trial: evolocumab has heart benefits and does not increase diabetes risks | IRIS trial: secondary analysis suggests that diabetes drug pioglitazone might benefit high-risk stroke patients
- Conference spotlight - News and notes from the EASD annual scientific meeting | J-DOIT3: a randomised, controlled trial of intensive therapy in type 2 diabetes | TOSCA.IT: pioglitazone in head-to-head trial with sulfonylurea is no better for heart outcomes | ACE: acarbose delays diabetes onset but fails to reduce cardiovascular events |EXSCEL: extended-release exenatide falls short of showing any extra benefits, but does demonstrate safety | Nutrition: sodium intake and sugar substitutes in the spotlight for type 2 diabetes risk | Obese wives increase risk of diabetes in husbands
- DOI: https://doi.org/10.2337/cd17-0110
- PDF: December 2017—Diabetes is Primary - News and Notes for Primary Care Providers
- In focus: digital diabetes lifestyle interventions
- “Spaced education” for diabetes lifestyle interventions
- The message is key in online messaging
- Text messaging works… if there are enough of them
- Diagnostics: A1C screening might miss prediabetes and diabetes
- The case of the missing microbes
- How to get results in 12 weeks: messaging plus other measures can reduce A1C quickly
- CRISPR-edited skin grafts to deliver glucagon-like peptide 1 and control blood glucose in diabetes
- ADA News
- Diabetes is Primary program updates providers on the front line of diabetes care
- Do national programs need and electronic health approach to improve outcomes?
- National standards for diabetes education support ehealth-based interventions
- Diabetes: there’s an app for that
- Self-reporting of patient data: a lost cause?
- DOI: https://doi.org/10.2337/cd17-0102
- PDF: October 2017—Diabetes is Primary - News and Notes for Primary Care Providers
Diabetes Spectrum - Diabetes is Primary: News and Notes for Primary Care Providers
Diabetes Spectrum focuses on strategies to individualise treatments and care for people with diabetes. In particular, the journal has a focus on diabetes self-management and education towards care.
As with the Diabetes is Primary section in Clinical Diabetes, the version for Diabetes Spectrum provided a quarterly digest of the latest research relevant for the focus of the journal.
2018 (vol 31, issues 1 - 4)
- From the Journals - Focus on diabetes distress | Diabetes distress can be reduced, according to trial data | Analysis supports distress intervention | Intervention to prevent diabetes distress? So far, so good | Ethnic minorities may be more likely to experience diabetes distress | Emotional reactions, distress also linked to prediabetes diagnosis | Language matters in diabetes care | Insurance gaps continue to affect type 1 diabetes outcomes
- ADA News
- Treatments and Therapies - Early type 1 diabetes diagnosis linked to reduced life expectancy and heart risks | Insulin pens and diabetes drugs added to safety watch list
- Marketplace - Freestyle Libre approved for 14-day wear, found to be cost effective | Android version of InPen insulin pen/mobile application wins approval | New mobile app on diabetes care offers continuing medical education credits
- Conference Spotlight - Little net cardioprotective benefit from daily aspirin and no overall benefit from Omege-3 fatty acid supplementation in people with diabetes
- DOI: https://doi.org/10.2337/ds18-0061
- PDF: November 2018—Diabetes is Primary - Timely news for the multidisciplinary care team
- From the Journals - Fasting glucose misses prediabetes; make A1C standard for prediabetes | Diabetes screening criteria miss up to half of prediabetes and diabetes cases | Screening lowers healthcare costs
- Treatments and therapies - “Fat but fit” again in the spotlight | Community healthcare worker-lad interventions can improve A1C
- Conference spotlight - Is free food the solution to diabetes?
- ADA News
- Marketplace - Dual-hormone closed-loop system reduces hypoglycemia | Most diabetes apps lack evidence | Artificial intelligence-based device for diabetic retinopathy screening approved
- DOI: https://doi.org/10.2337/ds18-0043
- PDF: August 2018—Diabetes is Primary - Timely news for the multidisciplinary care team
- From the Journals - Malnutrition worsens mortality risk in older adults with diabetes | Study confirms success of a consultation model for diabetes care
- Treatments and therapies - De-intensification of glucose-lowering drugs may be advisable in some elderly patients | Culturally-appropriate diabetes eduction improves outcomes
- Coding, regulations and reimbursements - High-deductible health plans’ effects on utilisation may differ based on member income | Better dosing guidelines needed for prescription drugs used in children with obesity
- Conference Spotlight - Very-low calorie diets may increase short-term heart risks
- ADA News
- Marketplace - Use of continuous glucose monitoring systems reduces hypoglycemia events | Consumer wearables offer benefits for people with diabetes
- DOI: https://doi.org/10.2337/ds18-0012
- PDF: May 2018—Diabetes is Primary - Timely news for the multidisciplinary care team
- From the Journals - Remission of type 2 diabetes with radical weight loss | Hong Kong type 2 diabetes management program is effective | Cost effectiveness of RAMP-DM | Personalised A1C targets may save money and improve quality of life
- Treatments and Therapies - Type 1 or type 2 diabetes in adults? | Type 2 or type 3C diabetes in adults?
- Conference spotlight - Benefits of bariatric surgery in patients with type 2 diabetes
- ADA News
- Coding, regulations and reimbursements - Diabetes prevention program added as a Medicare benefit
- Marketplace - ADA/EASD joint statement on CGM technologies: progress still needed
- DOI: https://doi.org/10.2337/ds17-0083
- PDF: February 2018—Diabetes is Primary - Timely news for the multidisciplinary care team